Soon after finishing is PhD in the domain of Cell and Molecular Biology, Tristan created a first Biotech company (PX Therapeutics) in 2000. This first start-up developed to a level where it exceed 50 employees and was then sold to a pharmaceutical company in 2012. In 2013, in collaboration with the CEA Grenoble and a group of experienced technologist and entrepreneurs, he launched a new deep tech project at the interface of Nanotech, Biotech and advanced data analytics technologies. This initiative gave rise to the creation of Aryballe (2014) which is developing a very original Bio Sensor applied to the analysis of smells. NeOse, the first product of the company is the first portable and universal odor sensor and is used by different industries from Food and Cosmetics to Automotive, Consumer Electronics and Health. The company has raised more than 20 M€ and is now the leader of the nascent industry of Digital Olfaction. In parallel, Tristan has been involved in the creation and development of several start-ups.